"So Vaisnava is always sorry for the rascals in the world. Otherwise he has nothing to be unhappy. He can sit down anywhere; he can sleep anywhere; he can eat anything. He doesn't require anyone's help. He... As Krishna is self-sufficient, similarly, Krishna, not exactly like that, but a Vaisnava is also self-sufficient, depending only on Krishna. That is Vaisnava. So he has nothing to lament or nothing to regret. He is always pleased in the service of the Lord, but he is always sorry for the conditioned souls who are suffering the material pangs on account of ignorance."
(Srila Prabhupada lecture, Mayapur, February 10, 1976)